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This function estimates the adjacency matrix of a ZINB model given a matrix of counts, using the optim function. Uses BiocParallel for parallelization.

Usage

zinb0.noT(X, maxcard, alpha, extend, nCores = 1)

Arguments

X

the matrix of counts (n times p).

maxcard

the uper bound of the cardinality of the conditional sets K

alpha

the significant level of the tests

extend

if TRUE it considers the union of the tests, otherwise it considers the intersection.

nCores

number of cores for parallelization

Value

the estimated adjacency matrix of the graph.

Details

This approach assumes that the structure of the graph only depends on the mean parameter, treating zero inflation as a technical noise effect. We call this model zinb0.